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Active Not Recruiting NCT06958367

Effect of Dexmedetomidine on Acute Kidney Injury After Ascending Aortic Surgeries

Conditions: Aki After Ascending Aortic Surgeries

Sex: All

Ages: 21 Years – 70 Years

Healthy volunteers: Yes

Phase: PHASE1

Enrollment: 78

Sponsor: Ain Shams University

Location: AIN shams university Cairo Egypt

Summary

Acute kidney injury (AKI) is a frequent and serious complication after ascending aortic surgeries requiring cardiopulmonary bypass (CPB). Dexmedetomidine, a selective α-2 adrenoreceptor agonist, may reduce AKI because of its sympatholytic and anti-inflammatory effects against ischaemia reperfusion injury. We investigate the effect of dexmedetomidine administration on AKI after ascending aortic surgeries requiring CPB in a placebo-controlled randomised controlled trial.

Eligibility Criteria

Inclusion Criteria: * ●Age: 20-70 yrs * Scheduled for aortic surgery under CPB Exclusion Criteria: * ●Patient refusal to participate * Congestive heart failure with a left ventricular ejection fraction \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06958367). StuddyBuddy aggregates publicly available trial information.