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Active Not Recruiting
NCT06902688
Timely Ordering of Pharmacogenetic Testing
Conditions: Machine Learning, Prediction Models, Pediatrics, Precision Medicine
Sex: All
Ages: 6 Months – 18 Years
Healthy volunteers: No
Phase: NA
Enrollment: 275
Sponsor: The Hospital for Sick Children
Location: The Hospital for Sick Children Toronto Ontario
Summary
The goal of this trial is to learn if a machine learning (ML) model can help optimize drug therapy in the pediatric population. The main question\[s\] it aims to answer are whether a machine learning model predicting receipt of a targeted medication within the next three months:
* Increases the offering of pharmacogenetic testing prior to receipt of a targeted medication
* Increases the number of patients with pharmacogenetic results prior to receipt of a targeted medication
* Increases the number of patients who have alteration in medication choice or dose based on pharmacogenetic results
This trial only focuses on the prediction and provision of participants with a high-risk of receiving a medication with a pharmacogenetic indication in the next three months.
Eligibility Criteria
Inclusion Criteria:
* Inpatient at The Hospital for Sick Children
* Between 6 months to 18 years old
Exclusion Criteria:
* Prior pharmacogenetic testing and/or prior receipt of a targeted medication
* Current Intensive Care Unit (ICU) admission
* Expected hospital discharge is prior to midnight on the day of admission
Source: ClinicalTrials.gov (NCT06902688). StuddyBuddy aggregates publicly available trial information.