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Active Not Recruiting
NCT06886451
Vomiting Prevention in Children With Cancer
Conditions: Chemotherapy Induced Nausea and Vomiting, Quality of Life (QOL), Pediatric Cancer
Sex: All
Healthy volunteers: No
Phase: NA
Enrollment: 1332
Sponsor: The Hospital for Sick Children
Location: The Hospital for Sick Children Toronto Ontario
Summary
The goal of this single arm trial is to learn if a machine learning (ML) model predicting the risk of vomiting within the next 96 hours will impact vomiting outcomes in inpatient cancer pediatric patients.
The main questions it aims to answer are whether an ML model predicting the risk of vomiting within the next 96 hours will:
Primary
1\. Reduce the proportion with any vomiting within the 96-hour window
Secondary
1. Reduce the number of vomiting episodes
2. Increase the proportion receiving care pathway-consistent care
3. Impact on number of administrations and costs of antiemetic medications
Newly admitted participants will have a ML model predict the risk of vomiting within the next 96 hours according to their medical admission information. The prediction will be made at 8:30 AM following admission. Pharmacists will be charged with bringing information about patients' vomiting risk to the attention of the medical team and implementing interventions.
Eligibility Criteria
Inclusion Criteria:
* All pediatric patients admitted to the oncology service at SickKids
Exclusion Criteria:
* Pediatric patients admitted to the oncology service at SickKids that are discharged prior to prediction time
Source: ClinicalTrials.gov (NCT06886451). StuddyBuddy aggregates publicly available trial information.