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Completed
NCT06837519
Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery
Conditions: Lidocaine, Dexmedetomidine, Infusion, Perioperative Pain, Video-Assisted Thoracoscopic Surgery
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 75
Sponsor: Ain Shams University
Location: Ain Shams University Cairo
Summary
This study aims to compare lidocaine and dexmedetomidine infusion and their combination on perioperative pain in patients undergoing video-assisted thoracoscopic surgery.
Eligibility Criteria
Inclusion Criteria:
* Age ≥18 years old.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status of I, II.
* Patients undergoing video-assisted thoracoscopic surgery (VATS) under general anesthesia.
Exclusion Criteria:
* Hypersensitivity to any of the used drugs.
* Coagulation disorder.
* Body mass index \>35 kg/m2.
* History of chronic pain requiring daily opioids/steroids/clonidine/other α2 agonist/analgesics or any drugs acting on the central nervous system during the previous 2 weeks, and drug/alcohol abuse.
* Contraindication to the use of local anesthetics.
* Cardiovascular disease.
* Severe respiratory, renal or hepatic impairment.
* Insulin-dependent diabetes mellitus.
* Central nervous system or psychiatric disease.
Source: ClinicalTrials.gov (NCT06837519). StuddyBuddy aggregates publicly available trial information.
