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NCT06833762
Clinical and CPET Parameters That Predict Improvement in Functional Capacity After TAVI
Conditions: Aortic Stenosis Disease
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 161
Sponsor: Hospital Clinic of Barcelona
Location: Hospital Clinic Barcelona Barcelona
Summary
Determining Clinical and Cardiopulmonary exercise testing Parameters that may predict Improvement in Capacity After Transcatheter Aortic Valve Implantation
Eligibility Criteria
Inclusion Criteria:
* All those patients ≥ 18 years of age with severe aortic stenosis approved for transfemoral TAVI.
Both sexes, male and female will be included in the study.
Exclusion Criteria:
Very severe aortic stenosis, defined as a valve area of ≤0.6 cm2
, mean gradient ≥60 mmHg or Vmax \>5 m/s
* Previous syncope
* Proven exercise-induced arrhythmias
* Previously known dynamic left ventricular outflow tract (LVOT) obstruction, defined as LVOT gradient of ≥ 30 mmHg by echocardiography
* Concomitant coronary artery disease pending percutaneous coronary intervention
* Inability to consent
* Physical limitation to perform an exercise test
* Non-elective procedure
* Valve-in-valve procedure
Source: ClinicalTrials.gov (NCT06833762). StuddyBuddy aggregates publicly available trial information.