Functional Cereal Products and Contribution to the Regulation of Metabolism and Obesity-induced Chronic Low-grade Inflammation.

Conditions: Hypercholesterolemia, Overweight/Obesity

Sex: All

Ages: 25 Years – 60 Years

Healthy volunteers: No

Phase: NA

Enrollment: 60

Sponsor: Harokopio University

Location: National and Kapodistrian University of Athens, School of Medicine Athens Attica

Summary

The goal of this clinical trial is to find out the possible beneficial effects of a white wheat bread enriched with oat beta-glucans on mildly hypercholesterolemic subjects with overweight/obesity. The main questions it aims to answer are: Does the enriched bread lower total and LDL-cholesterol levels as well as the levels of inflammatory factors of the participants? Does the enriched bread positively change the composition of gut microbiota? Researchers will compare the enriched bread to a common white wheat bread to see if the enriched bread provides additional effect beyond a hypocaloric dietary plan that the participants of both groups are going to follow. Participants will: Take the enriched or the common bread every day for 8 weeks. Visit the clinic once every 2 weeks for checkups and tests.

Eligibility Criteria

Inclusion Criteria: * no underlying diseases * with LDL-cholesterol levels between 115-150 mg/dL * with 25\

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06822621). StuddyBuddy aggregates publicly available trial information.