Indicators and Evaluation of Efficacy of Yin-nourishing and Fire-reducing Chinese Medicine for Girls With Rapid Progression of Early Puberty

Sex: Female

Ages: 8 Years – 9 Years

Healthy volunteers: No

Phase: PHASE4

Enrollment: 80

Sponsor: Children's Hospital of Fudan University

Location: Children's Hospital of Fudan University Shanghai Shanghai Municipality

Summary

1\. Evaluate whether AMH and SHBG have differential expression before and after the diagnosis of rapid and slow progression types of early puberty and whether this difference has a predictive effect on the rapid progression type. 2. Assess the therapeutic effect of nourishing yin and purging fire traditional Chinese medicine on girls with rapid progression type of early puberty providing a standardized clinical basis for the formulation of diagnostic and treatment guidelines (or protocols) for the rapid progression type of early puberty using traditional Chinese medicine

Eligibility Criteria

Inclusion Criteria: * Girls with an onset age \>8 years and ≤9 years; * Breast bud Tanner stage II breast bud diameter \

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06820931). StuddyBuddy aggregates publicly available trial information.