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NCT06753409
Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery
Conditions: Postoperative Acute Kidney Injury
Sex: All
Ages: 18 Years – 70 Years
Healthy volunteers: No
Phase: NA
Enrollment: 162
Sponsor: Assiut University
Location: Assiut University Hospitals Asyut
Summary
This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a decrease in postoperative complications, particularly acute kidney injury (AKI).
Eligibility Criteria
Inclusion Criteria:
1. Patients scheduled for major abdominal surgery lasting more than 2 hours under general anesthesia.
2. American Society of Anesthesiologists Physical Status (ASA) score I-III.
3. Age range of 18-70 years.
4. Both male and female patients.
Exclusion Criteria:
1. Emergency surgeries.
2. Uncontrolled hypertension (systolic blood pressure \>150 mm Hg) despite medication.
3. Recent acute cardiovascular events, including heart failure or acute coronary syndrome.
4. Chronic kidney disease with a glomerular filtration rate \2N, elevated bilirubin, or PT \
Source: ClinicalTrials.gov (NCT06753409). StuddyBuddy aggregates publicly available trial information.