Repetitive Transcranial Magnetic Stimulation Therapy in Spinal Cord Injury Related Neuropathic Pain

The aim of our study is to investigate the effect of different protocols of high-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) therapy added to the rehabilitation program on neuropathic pain,depression, quality of life and quality of sleep compared to each other and placebo group in participants with spinal cord injury.

Inclusion Criteria: Aged 18-75 years Physician-diagnosed spinal cord injury for at least 3-months Neuropathic pain for at least 3-months Pain not attributable to any other conditions Exclusion Criteria: * Having an important comorbid disease such as severe heart disease (aortic stenosis, angina, hypertrophic cardiomyopathy, uncontrolled hypertension,arrhythmia, pacemaker) * Neurodegenerative disease * Epilepsy * History of antiepileptic drug use * Cognitive dysfunction * Lower extremity peripheral nerve injury * Increased intracranial pressure or uncontrolled migraine * Infection on the skin in the application area. * Having a brain lesion or a history of drug use that will affect the seizure threshold. Any TMS-related contraindications, for example: * Pacemaker * Metallic implant * Previous seizure * Psychiatric disorders (excluding depression and anxiety) * Malignancy * Current pregnancy