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NCT06706310
Evaluate TQ-A3334 Combined Nucleoside (Acid) Analogs in the First Treatment/Treatment of Chronic HBV Infection
Conditions: Chronic Hepatitis B
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Phase: PHASE2
Enrollment: 116
Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Location: The First Affiliated Hospital of Chongqing Medical University Chongqing Chongqing Municipality
Summary
This study uses random, double -blindness, placebo control, and phase multi -center test design. All subjects who meet the standards receive TQ-A3334 per tablet/placebo nucleoside (acid) analog. A total of 116 subjects are needed.
Eligibility Criteria
Inclusion Criteria:
Those who meet all the selected standards below can enter the group test:
* The subject can communicate well with the researchers and understand and comply with the various items in this study, understand and sign the consent of informed consent;
* 18-65 years old (including the boundary value), and men and women are not limited (calculated based on the date of signing the consent of informedness);
* Serum virus standard: serum HBSAG positive for more than 6 months or more than 6 months chronic Evidence of HBV infection.
* No obvious liver cirrhosis is judged by researchers;
Those who have been treated after treatment need to meet the following conditions:
* The subject must receive oral nucleoside (acid) drug treatment before screening ≥6 months and the stable treatment plan before the screening period is ≥3 months;
* Historian history records of the HBV DNA \
Source: ClinicalTrials.gov (NCT06706310). StuddyBuddy aggregates publicly available trial information.