Gonadal Tissue Cryopreservation for Fertility Preservation in Children With a Disorder of Sex Development

The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer). This study involves the storage of gonadal tissue that is being removed for medical reasons (e.g. prevention of cancer development). It includes the processing and freezing of this gonadal tissue, hopefully for potential future use. The tissue will then be stored long-term until the child wishes to try to use the tissue.

Inclusion Criteria: * Individual \< 30 years of age * Children diagnosed with a disorder of sex development who have any risk for malignancy in their gonadal tissue or will have their gonads removed for another clinical indication Exclusion Criteria: * Pregnant children * Patients likely to retain inherent fertility and reproductive function * Children deemed high risk for perioperative complications * Patients 12-18 unable to provide assent (i.e. significant psychiatric problems/cognitive delay) * Patients 18 and older unable to provide consent (i.e. significant psychiatric problems/cognitive delay)