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Completed
NCT06655025
The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery
Conditions: Cardiac Surgery, Postoperative Cognitive Dysfunction, Neurologic Manifestations
Sex: All
Healthy volunteers: Yes
Phase: NA
Enrollment: 32
Sponsor: Sohag University
Location: Sohag University Sohag
Summary
To assess the impact of Dexmedetomidine on postoperative cognitive function and serum Neuron Specific Enolase levels as an indicator of neuronal injury in patients undergoing open heart surgery
Eligibility Criteria
Inclusion Criteria:
* Patients of both sexes undergoing elective open-heart surgery
Exclusion Criteria:
* Patients with a history of neurological disorders, severe renal or liver dysfunction, or contraindications to Dexmedetomidine as in patients with known QT prolongation, a history of other arrhythmias, symptomatic bradycardia, hypokalemia, or hypomagnesemia, and in patients receiving other drugs known to prolong the QT interval.
Patients with cognitive impairment, mental and psychological illness and chronic alcoholics, drug addicts, abuse of psychotropic substances, illiterate education
Source: ClinicalTrials.gov (NCT06655025). StuddyBuddy aggregates publicly available trial information.
