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Recruiting
NCT06628570
Screening Strategies Among High-risk Populations for Anal Cancer
Conditions: Neoplasms, HPV-Related Anal Squamous Cell Carcinoma
Sex: All
Ages: 30 Years – 80 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 500
Sponsor: Lisa Flowers
Location: University of Miami Miller School of Medicine-Sylvester Cancer Center Miami Florida
Summary
The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.
Eligibility Criteria
Inclusion Criteria:
* 30-80 years of age
* Individuals with chronic impaired immune status
* History of lower genital tract neoplasia (LGTN), Zubrod Performance Status of 0-2
Exclusion Criteria:
* Patients treated for aHSIL less than 6 months before screening
* History of anal cancer and pregnant women.
Source: ClinicalTrials.gov (NCT06628570). StuddyBuddy aggregates publicly available trial information.
