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Completed
NCT06581731
Comparison of Remifentanil With a Combination of Remimazolam and Dexmedetomidine for Awake Tracheal Intubation
Conditions: Difficult or Failed Intubation, Sedative Adverse Reaction
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: No
Phase: NA
Enrollment: 64
Sponsor: Nanjing First Hospital, Nanjing Medical University
Location: Nanjing First Hospital Nanjing Jiangsu
Summary
Awake fiberoptic intubation (AFOI) requires airway surface anesthesia to inhibit pharyngeal reflex, glottis closure reflex, and cough reflex. Additionally, the use of sedative drugs can enhance patient comfort and tolerance, reduce anxiety, and eliminate harmful effects on systemic hemodynamics.The objective of this study is to compare the safety and efficacy of remifentanil alone versus a combination of dexmedetomidine and remifentanil for sedation during conscious tracheal intubation.
Eligibility Criteria
Inclusion Criteria:
1. Patients scheduled for elective open cervical spine surgery.
2. Age 18-65 years old
3. ASA classifications of I-III
4. BMI\
Source: ClinicalTrials.gov (NCT06581731). StuddyBuddy aggregates publicly available trial information.
