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Completed
NCT06450132
Changes in Eye Shape With Myopia Management Interventions
Conditions: Myopia
Sex: All
Ages: 21 Years – 30 Years
Healthy volunteers: Yes
Phase: PHASE4
Enrollment: 75
Sponsor: Ohio State University
Location: The Ohio State University Columbus Ohio
Summary
The goal of this clinical trial is to study changes in eye shape of nearsighted young adults using low-dose atropine eye drops or soft multifocal contact lenses. The main questions it aims to answer are:
* do low-dose atropine and soft multifocal contact lenses affect the shape of the peripheral eye?
* are changes in peripheral eye shape from these interventions influenced by changes in the focusing system of the eye?
Participants will:
* have multiple different types of photos taken
* have their prescription for glasses/contacts checked
* have their eye health checked, including the use of dilating eye drops
* be randomly assigned to use eye drops every night or wear special contact lenses daily instead of their typical contacts
* will complete five study visits over the course of 12 months
Researchers will compare young adults using low-dose atropine to those wearing soft multifocal contact lenses and to those using no intervention to see if using these interventions affects retinal shape.
Eligibility Criteria
Inclusion Criteria:
* best corrected visual acuity of 20/25 or better in each eye
* nearsighted
* current contact lens wearer
* normal binocular vision (to be determined by an examiner at the first study visit)
Exclusion Criteria:
* eye diseases (including lazy eye or eye turn)
* pregnant, nursing, or planning a pregnancy in the next 12 months
* history of refractive surgery (e.g., LASIK)
* history of myopia control treatment
* sensitivity to anesthetics or preservative in eye drops
* difficulty with pupillary dilation
Source: ClinicalTrials.gov (NCT06450132). StuddyBuddy aggregates publicly available trial information.