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NCT06355050
Ultrahypofractionated, Adaptive Radiation Therapy of Prostate Cancer
Conditions: Prostate Cancer, Adaptive Radiotherapy, Quality of Life
Sex: Male
Ages: 18 Years – 120 Years
Healthy volunteers: No
Enrollment: 150
Sponsor: Jena University Hospital
Location: Department of Radiotherapy and Radiation Oncology, Jena University Hospital Jena
Summary
In this prospective, multi-center cohort study, the tolerability and quality of life during ultrahypofractionated radiotherapy (RT) of early stage prostate cancer is surveyed at several institutions in Germany. Radiotherapy is delivered by an online-adaptive RT device (Varian Ethos), which is able to correct daily variations in anatomy and to adjust the irradiation plan accordingly. A digital patient questionnaire is used to asses quality of life longitudinally. Quality of life (QoL) and toxicity profiles will be correlated with planning parameters and compared to retrospective cohorts of patients who underwent normofractionated RT or moderately hypofractionated RT, respectively.
Eligibility Criteria
Inclusion Criteria:
* no androgen deprivation therapy within the last 2 months prior to RT
* good performance status (Eastern Cooperative Oncology Group, ECOG, 0/1)
* no secondary malignancy
Source: ClinicalTrials.gov (NCT06355050). StuddyBuddy aggregates publicly available trial information.
