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Completed NCT06249386

Adapting and Piloting Behavioral Activation for Veterans With Alcohol Use Disorder and Posttraumatic Stress Disorder

Conditions: Alcohol Use Disorder, Posttraumatic Stress Disorder

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 10
Sponsor: RTI International

Location: Duke University School of Medicine Durham North Carolina

Summary

The goal of this clinical trial is to compare an adaptation of Behavioral Activation, a behavioral intervention, to Relapse Prevention treatment, another behavioral intervention, in a sample of U.S. military veterans with co-occurring alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD). The primary aims of this study are to: 1. Adapt Behavioral Activation to treat veterans with AUD/PTSD, 2. Evaluate the feasibility, acceptability, and preliminary effects of Behavioral Activation for AUD/PTSD, and 3. Explore geospatial analysis as a new method for measuring AUD/PTSD recovery. Participants will complete self-report and interview measures immediately before and immediately after treatment. Participants will also be asked to participate in passive geospatial assessment for 14-day periods immediately before and immediately after treatment. Participants will be randomized to treatment condition, which involves 8 sessions of either Behavioral Activation or Relapse Prevention, delivered individually by a trained study therapist.

Eligibility Criteria

Inclusion Criteria: 1. Be a U.S. veteran, 2. Be at least 18 years old, 3. Meet Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for current AUD, 4. Report 3+ heavy drinking days (5+ drinks for men/4+ drinks for women) or 1+ heavy drinking week (15+ drinks men/8+ drinks women) in the past 30 days, 5. Meet DSM-5 criteria for current PTSD or satisfy the definition of current subthreshold PTSD (i.e., up to one of symptom clusters B-E may fall below diagnostic threshold), 6. Be fluent and literate in English, and 7. Be able to provide voluntary, informed consent to participate. Exclusion Criteria: 1. Current mania/hypomania or current psychosis, 2. Lifetime alcohol withdrawal-related seizures, delirium, or hallucinations, 3. Prior inpatient alcohol withdrawal management, 4. Current DSM-5 severe drug use disorder (DUD) except for severe tobacco use disorder, 5. Psychotropic (including alcohol abstinence) medication changes within 30 days of study enrollment or plans to change medications during the study, 6. Current/planned non-study BA for any disorder during the study, or 7. Current/planned evidence-based psychotherapy for AUD, PTSD, or DUD during the study.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT06249386). StuddyBuddy aggregates publicly available trial information.