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Completed
NCT06247891
Endocytoscopy of Upper Gastrointestinal Tract in Acute Graft-versus-host Disease: a Pilot Study
Conditions: Endocytoscopy
Sex: All
Ages: 14 Years – N/A
Healthy volunteers: No
Enrollment: 14
Sponsor: Ruijin Hospital
Location: Ye Zhao Shanghai
Summary
The goal of this clinical trial is to test the assess the diagnostic effectiveness of endocytoscopy in patients with underlying UGI aGvHD. The main question it aims to answer is: the effectiveness of ECS for diagnosing UGI aGvHD. Participants will undergo endoscopy, endocytoscopic evaluation and biopsy simultaneously. If there is a comparison group: Researchers will compare endoscopic, endocytoscopic and pathologic findings of these patients.
Eligibility Criteria
Inclusion Criteria:
* aged ≥ 14 years
* developed UGI symptoms within first three months after engraftment or during the tapering of immunosuppressive agents
Exclusion Criteria:
* \< 14 year
* with underlying gastrointestinal disease before allo-HSCT
* incomplete medical information
Source: ClinicalTrials.gov (NCT06247891). StuddyBuddy aggregates publicly available trial information.