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Completed
NCT06216015
Exercise Training and Kidney Transplantation
Conditions: Solid Organ Transplant Rejection, Chronic Kidney Failure, Quality of Life, Inflammation, Muscle Weakness
Sex: All
Ages: 18 Years – 60 Years
Healthy volunteers: No
Phase: NA
Enrollment: 345
Sponsor: Hugo de Luca Correa
Summary
The goal of this clinical trial is to investigate the physiological and molecular effects of exercise training in transplant recipients. The main questions it aims to answer are:
1. Can exercise training improve physical fitness and muscle strength in transplant recipients?
2. Can exercise training modulate inflammatory profile, hormones, lipid profile, and exercise-induced molecules in transplant recipients?
3. Can exercise training improve blood pressure and endothelial health in transplant patients?
Participants will be invited to an exercise training program 6-month after their transplant surgery. Body composition, physical assessment, and blood draw will be assessed at baseline and 24-weeks after exercise or control regimen.
Researchers will compare exercise group vs. routine care group to see if exercise training impact the health-related outcomes of this population.
Eligibility Criteria
Inclusion Criteria:
* Medical Authorization:
* Stable Health Status
* Medication Consistency
* No History of Severe Cardiovascular Events
* No Major Orthopedic Issues
* Non-Smokers or Consistent Smoking Habits
* Ability to Comply with Study Protocols
Exclusion Criteria:
* Inability to Comply
* Cognitive disorders
* Unwillingness to Continue
* Unstable Health Conditions
* Physical limitations during the protocol
Source: ClinicalTrials.gov (NCT06216015). StuddyBuddy aggregates publicly available trial information.