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Recruiting
NCT06160635
D-SOLVE Cohorts (Cohort A and B)
Conditions: HDV, HDV Infection, Chronic Liver Disease
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 750
Sponsor: Hannover Medical School
Location: Hannover Medical School, Department of Gastroenterology, Hepatology, Infectious Disease and Endocrinology Hanover
Summary
Hepatitis D is by far the most severe form of chronic viral hepatitis, frequently leading to liver failure, hepatocellular carcinoma and death. Hepatitis D is caused by coinfection Hepatitis D is caused by co-infection with hepatitis B virus (HBV) and hepatitis D virus (HDV).
This multicenter cohort should enable a comprehensive and unbiased biomarker screening of well-defined HDV-infected patients, followed by mechanistic studies to determine the functional role of distinct molecules. Patient surveillance strategies and antiviral treatment approaches could be personalized which should reduce clinical and social disease burden, improve quality of life and save direct and indirect costs caused by HDV infection.
Eligibility Criteria
Inclusion Criteria:
* Anti-HDV positive
* ≥18 years old
* Sex: m/f/d
* Informed consent for prospective procedures
Exclusion Criteria:
* Anti-HDV negative
Source: ClinicalTrials.gov (NCT06160635). StuddyBuddy aggregates publicly available trial information.
