← Back to all trials
Recruiting
NCT06154083
INtensity of OVarian Stimualtion and Euploid Embryos
Conditions: Fertility
Sex: Female
Ages: 38 Years – 42 Years
Healthy volunteers: No
Phase: PHASE4
Enrollment: 110
Sponsor: Fundación Santiago Dexeus Font
Location: Hospital Universitario Quiron Dexeus Barcelona
Summary
This randomized trial was designed as a no-inferiority trial aiming to evaluate if the intensity of stimulation (a milder vs a more intense approach) may have an impact on the number of euploid embryos and the morpho kinetic parameters in advanced age women undergoing PGT-A with a PPOS protocol.
Eligibility Criteria
Inclusion Criteria:
* Infertile patients with indication for IVF
* Undergoing preimplantation genetic screening cycles
* AMH \>= 1.5 ng/ml and \< 3.5 ng/ml (AMH result of up to one year will be valid)
* BMI 18.5 - 30 Kg/m2
Exclusion Criteria:
* Severe male factor requiring TESE (testicular sperm extraction)
* AMH \< 1.5 ng/ml or \>= 3.5 ng/ml
* Administration of any other drug potentially interfering with the treatment
* Contraindication for hormonal treatment
* Recent history of severe disease requiring regular treatment (clinically significant concurrent medical condition that could compromise subject safety or interfered with the trial assessment).
* Monogenic disease to be detected with PGT-M
Source: ClinicalTrials.gov (NCT06154083). StuddyBuddy aggregates publicly available trial information.