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NCT06077981
Comparison of 0.4% Hyaluronic Acid Solution Versus Hydroxyethylamide Solution in Submucosal Endoscopic Resections
Conditions: Esophageal Neoplasms, Endoscopic Mucosal Resection, Hyaluronic Acid
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 30
Sponsor: Instituto do Cancer do Estado de São Paulo
Location: Instituto do Câncer do Estado de São Paulo São Paulo São Paulo
Summary
This is a randomized, single-center clinical trial that will compare the efficacy of two substances used in the submucosal cushion formation stage of endoscopic submucosal resections of early esophageal malignant neoplasms. Such substances are hyaluronic acid in the form of TS-905 Blue Eyeₒ and hydroxyethylamide (Voluven®).
Eligibility Criteria
Inclusion Criteria:
* Patients over 18 years of age
* Superficial esophageal adenocarcinoma or squamous cell carcinoma with indication of ESD after discussion in a multidisciplinary oncological board
* Signed informed consent form
Exclusion Criteria:
* Residual or recurrent esophageal lesions
* Ulcerated esophageal lesions
* Patients with severe cardiovascular, kidney or liver disease
* History of hypersensitivity to hyaluronic acid
* Pregnant or lactating women
Source: ClinicalTrials.gov (NCT06077981). StuddyBuddy aggregates publicly available trial information.
