← Back to all trials
Completed
NCT05956964
NM Balance Regulation With ULLS and Loss of Sleep
Conditions: Muscle Weakness, Quadriceps Muscle Atrophy, Sleep Disturbance
Sex: All
Ages: 18 Years – 50 Years
Healthy volunteers: Yes
Phase: NA
Enrollment: 16
Sponsor: Lance Bollinger
Location: University of Kentucky Lexington Kentucky
Summary
The goal of this trial is to learn about how restricted sleep and not bearing weight on the leg affects muscle strength and posture control. Participants will walk exclusively on one leg, sleep at differing intervals, and complete posture tests, muscle strength tests, and muscle imaging. Researchers will compare adequate sleep and restricted sleep to see if muscle strength and posture are affected.
Eligibility Criteria
Inclusion Criteria:
* Age between 18 and 50 years
* Regularly engaging in aerobic exercise (\> 150min/wk) and resistance exercise (\>1 time per week) for the past 12 months
* Regularly sleep at least 7 hours per night
Exclusion Criteria:
* Age \< 18 or \> 50 years
* Height between \ 90cm (F) and \< 75cm or \> 100cm (M)
* Body mass index \< 18.5 or \> 27.5
* Do not regularly sleep between 7 and 9 hours each night
* Have a known sleep disorder
* Not regularly engaging in exercise for previous 12 months
* Blood clotting disorder
* Heart arrhythmia
* Implanted device which could negatively be affected by electrical impulse or strong magnetic field such as pacemaker, internal defibrillator, or cochlear implant
* Diagnosed cardiovascular, pulmonary, renal, or metabolic disease
* Pregnancy (within previous 6 months)
* Oral contraceptive use (within previous three months)
* High resting blood pressure (\>140 systolic and/or \> 90 diastolic)
* Currently or previously undergone gender-affirming therapy (hormone therapy or sexual reassignment surgery)
* Low back or leg injury in previous 6 months
* Currently taking medication to assist with sleep
* Muscle, bone, or joint injury that limits physical activity within previous 6 months
* Neurological disorder which affects balance (such as multiple sclerosis or Parkinson's disease)
Source: ClinicalTrials.gov (NCT05956964). StuddyBuddy aggregates publicly available trial information.