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Recruiting
NCT05932745
Effects of Novel E-cigarette Constituents on Adults TCORS 3.0
Conditions: Nicotine Use Disorder
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 66
Sponsor: Yale University
Location: JB Pierce Lab New Haven Connecticut
Summary
This study is an examination of the influence of cooling components of WS-3, WS-23, and menthol on the appeal and addiction potential of nicotine-containing e-liquids among adults.
Eligibility Criteria
Inclusion Criteria:
* 18 years or older
* Able to read and write
* Some current e-cigarette use
* Urine cotinine ≥200ng/ml
* Willing to abstain from tobacco/nicotine use 2 hours prior to sessions
Exclusion Criteria:
* Current use of non-prescription substances besides nicotine, marijuana, alcohol
* Any significant current medical or psychiatric condition
* Known hypersensitivity to propylene glycol
* Pregnant or lactating females
* Uncontrolled asthma
* Nut/e-liquid flavorant allergy
* Current marijuana (tetrahydrocannabinol) vaping + E-cigarette or vaping use Associated Lung Injury (EVALI) symptoms
* Dislike of menthol flavor
Source: ClinicalTrials.gov (NCT05932745). StuddyBuddy aggregates publicly available trial information.