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Withdrawn NCT05930756

3-point vs 6-point GNRFA for Chronic KOA

Conditions: Osteoarthritis, Knee, Chronic Pain

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Sponsor: McMaster University

Location: St. Joseph's Healthcare Hamilton-Charlton Campus Hamilton Ontario

Summary

The goal of this clinical trial is to compare three-point and six-point Genicular Nerve Radiofrequency Ablation (GNRFA) in adults with chronic knee osteoarthritis (KOA). The main question it aims to answer is whether six- target GNRFA technique is more efficacious than standard three-target GNRFA technique in managing the pain and function of KOA. Consented patients who respond to a diagnostic block will be randomly assigned to either three-point or six-point GNRFA. Researchers will compare pain and function in these two groups.

Eligibility Criteria

Inclusion Criteria: * Age 18 years or older * Chronic knee pain for at least 3 months with radiological evidence of KOA graded 2-4 on the Kellgren-Lawrence scale as determined by a radiologist Exclusion Criteria: * unwilling, * unable to communicate in English, * have acute knee pain, * prior knee surgery, * allergies to local anesthetics, * chronic opioid consumption of daily morphine equivalent of \>30 mg for at least four weeks prior to procedure, * neurologic diseases affecting the lower limbs (i.e. previous CVA, MS), * connective tissue diseases affecting the knee, * treatment with intra-articular steroid injections and/or hyaluronic acid in the previous 3 months.

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05930756). StuddyBuddy aggregates publicly available trial information.