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Recruiting
NCT05864794
Value of Screening MRI Brain in Stage IV Non-small Cell Lung Cancer
Conditions: Non Small Cell Lung Cancer Metastatic
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: NA
Enrollment: 100
Sponsor: University Medical Center Groningen
Location: University Medical Center Groningen Groningen Provincie Groningen
Summary
Patients with newly diagnosed stage IV non-oncogene addicted NSCLC, who are fit for systemic treatment and don't have any symptoms of brain disease will undergo an MRI of the brain to screen for brain disease.
Eligibility Criteria
Inclusion Criteria:
* Histologically or cytologically confirmed stage IV metastatic NSCLC, not amenable to curative treatment.
* Fit for systemic treatment (PS 0-2) according to standard of care.
* No symptoms of brain disease disease assessed according to standard clinical care by the thoracic oncologist.
Exclusion Criteria:
* Prior/concomitant therapy for stage IV disease.
* Oncogenic diver mutation (e.g. EGFR, ALK, ROS1, RET, MET, and BRAF) with approved targeted treatment.
* Contraindications for MRI scan with contrast as per standard of care protocol of the institution.
Source: ClinicalTrials.gov (NCT05864794). StuddyBuddy aggregates publicly available trial information.
