← Back to all trials
Recruiting
NCT05856136
A Study to Investigate the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle
Conditions: Respiratory Function Loss, Respiratory Complication
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Phase: PHASE4
Enrollment: 69
Sponsor: Mayo Clinic
Location: Mayo Clinic Minnesota Rochester Minnesota
Summary
The purpose of this study is to evaluate opioid dose effects on the ability of the diaphragm muscle to generate higher force behaviors.
Eligibility Criteria
Inclusion Criteria:
\- Adult male and female patients undergoing lower extremity orthopedic surgery at the study institutions (St. Mary Hospital and Rochester Methodist Hospital within the Mayo Clinic Rochester hospital system).
Exclusion Criteria:
* Patients who refuse research participation.
* Patients who are pregnant.
* Patients with known pulmonary pathology (COPD, asthma requiring routine treatment).
Source: ClinicalTrials.gov (NCT05856136). StuddyBuddy aggregates publicly available trial information.
