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NCT05843214
Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements
Conditions: Neurological Complication
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: No
Enrollment: 230
Sponsor: Centre Hospitalier Universitaire de la Réunion
Location: CHU de la Réunion Saint-Pierre
Summary
Non-invasive neuromonitoring tools such as transcranial doppler, optic nerve envelope diameter measurement and quantitative pupillometry are routinely used in acute brain injured patients as part of multimodal neuromonitoring with the aim, among others, of detecting episodes of intracranial hypertension, each method allowing the study of one of the different pathophysiological mechanisms of its impact.
However, at present there is no data in the literature on the value of these non-invasive neuromonitoring tools in the management of patients undergoing controlled intracranial surgery.
The study aims to help the early detection of postoperative neurological deterioration.
Eligibility Criteria
Inclusion Criteria:
* Regulated intracranial surgery: scheduled \> 48 hours
* French-speaking patient
* No opposition from the patient or a relative when the patient is unable to consent
Exclusion Criteria:
* Chronic subdural haematoma
* Isolated cerebral endovascular procedure
* Stereotactic biopsy
* Scheduled ventriculoperitoneal shunt or isolated ventriculocisternostomy
* Specific non-inclusion criteria for quantitative pupillometry: known pupillary abnormalities, glaucoma, cataract surgery and any ocular surgery.
Source: ClinicalTrials.gov (NCT05843214). StuddyBuddy aggregates publicly available trial information.