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Completed
NCT05839990
Biomechanical Properties of the Human Ascending Aortic Wall in Aneurysm
Conditions: Ascending Aortic Aneurysm
Sex: All
Ages: 17 Years – 80 Years
Healthy volunteers: No
Phase: NA
Enrollment: 50
Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences
Location: Tomsk NRMC Tomsk
Summary
The aim of the study is to analyze the efficacy of the surgical tretment in patients with ascending aortic aneurysm and dilatation. And to assess rate of negative clinical scenarios in non-oparated patients with ascending aortic dilatation
Eligibility Criteria
Inclusion Criteria:
* Ascending aortic aneurysm (50 mm and more)
* Ascending aortic dilatation (45-49 mm)
Exclusion Criteria:
* Aortic dissection
* Patients with known/documented coagulopathy
* Oncological disease (high degrees)
* Severe chronic heart failure
* Refusal of surgical treatment
* Patients in renal failure or currently being treated with renal replacement therapy (RRT) or estimated glomerular filtration rate (eGFR) \< 30 ml/min/1.73m2
* Severe carotid disease, defined as: any patient with previously documented carotid stenosis of \> 70%, without neurological deficits; or carotid stenosis \> 50% with neurological deficits; or previous carotid endarterectomy or stenting
* Pre-existing severe neurological impairment or inability to accurately assess neurocognitive function as determined by the operating surgeon
Source: ClinicalTrials.gov (NCT05839990). StuddyBuddy aggregates publicly available trial information.