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NCT05775588
Long-term Effects of Endobronchial Valve Implantation on Cardiac Function and Skeletal Muscle Function
Conditions: Chronic Obstructive Pulmonary Disease
Sex: All
Ages: 18 Years – 90 Years
Healthy volunteers: No
Phase: NA
Enrollment: 100
Sponsor: China-Japan Friendship Hospital
Location: China-Japan Friendship Hospital Beijing Beijing Municipality
Summary
The goal of this type of study: clinical trial is to evaluate the effect of bronchial valve implantation on cardiac function and skeletal muscle function in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:evaluate the effect of bronchial valve implantation on cardiac function and skeletal muscle function.
Participants will undergo Lung volume reduction surgery with endobronchial valve implantation.
Eligibility Criteria
Inclusion Criteria:
* Patients with Chronic Obstructive Pulmonary Disease
* FEV1 ≤ 45% pred and FEV1/FVC\100% pred and RV\>175% pred
* CAT score≥18
* Emphysema damage\>50%
* Complete interlobar fissure \>95% based on quantitative analysis of CT measurement
* No smoking\>6 months
* Sign the informed consent form
Exclusion Criteria:
* PaCO2\>8.0 kPa, or PaO2\
Source: ClinicalTrials.gov (NCT05775588). StuddyBuddy aggregates publicly available trial information.
