Intratendinous Genipin Injection in Horses With Tendon Injuries

Our study is the first to use genipin, a naturally occurring collagen cross-linking agent, as a therapeutic agent to treat superficial digital flexor tendon (SDFT) injuries in horses. The promising approach of intratendinous genipin injection and tendon mechanical enhancement could be a viable alternative to current therapies for SDFT injuries.

Inclusion Criteria:clinical and sonographic evidence of a tendon injuryExclusion Criteria:in the final analysis, only superficial digital flexor tendon injuries were includedif follow-up was less than 12 m due to euthanasia, death or other reasons, horses were excluded from the study