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Active Not Recruiting NCT05753332

Association Between PM2.5 and Ferroptosis

Conditions: Exposure to Polluted Air

Sex: All
Ages: 18 Years – N/A
Healthy volunteers: 1
Enrollment: 60
Sponsor: Northern Jiangsu Province People's Hospital

Location: China

Summary

This cohort study aims to discover the possible effects of PM2.5 exposures on the Nrf2- dependent ferroptosis pathway. This observational cohort's main question is whether PM2.5 exposures will affect the Nrf2- dependent ferroptosis pathway.Participants will be divided into two groups: the control group and the air pollution to detect the biomarkers of the Nrf2- dependent ferroptosis pathway.

Eligibility Criteria

Inclusion Criteria:Aged over 18 years old living in this city for more than one year no exposure to any chemistry pollution beforeExclusion Criteria:Aged below 18 years old neurological disorders; endocrine diseases; cancer significant changes in biomarkers (TNF-α, Nrf2, SLC7A11, GPX4) at the beginning

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05753332). StuddyBuddy aggregates publicly available trial information.