Effect on Markers of Cardiovascular, Reproductive and Cancer Risk From Firefighting Training

Epidemiological studies based on Danish registries have observed that Danish male firefighters have more cardiovascular disease, infertility diagnose and a trend to increased risk of cancer than other Danish employed males. Firefighting activities include a combination of stressors such as strenuous work under heat, smoke and soot known to be able to affect cardiovascular and reproductive health, with smoke and soot also being known to increase the risk of cancer.The training facilities of real-fire extinguishing exercises in Denmark operate using wood or natural gas fire, which will have differential gradients of smoke, soot and possibly heat. The investigators will use different training conditions to create gradients of the different stressors and investigate health effects thereof. With this approach, the investigators expect to be able to evaluate the individual contribution of the different stressors in markers of cardiovascular, cancer and reproductive health risk. The project will include approx. 35 young conscript participants on a firefighting course, followed in four sessions, three firefighting training sessions under different fire conditions (no fire, wood fire and gas fire) and one control scenario.

The participants will be volunteers (both males and females) recruited among conscripts in training in a desirable involved group up to 35 individuals.Inclusion Criteria:legally competent,conscript subjects following a Rescue Specialist Educational courseExclusion Criteria:current smoking status,pregnancy,on prescribed medication,body mass index (BMI) bellow 19 or over 30,alcohol or drug abuse.