Physical Activity, Sedentary Behaviour and Cardiometabolic Health in Multiple Sclerosis

This study evaluates the association between sedentary behaviour, physical activity, and the cardiometabolic health of Multiple Sclerosis via several cardiovascular, metabolic and anthropometric parameters.

Inclusion Criteria:Relapse-remitting MS25-60 years oldEDSS < 5Sedentary behaviour (>9hours daily)Exclusion Criteria:<9h SB/day,experienced an acute exacerbation within 6 months before the start of the studyan expanded disability status scale (EDSS) score >5experimental drug use or medication changes in the last monthmedical conditions precluding PA participationalcohol abuse (>20 units/week)reported dietary habits or weight loss (>2kg) in the last month before the studyintention to start a new specific diet or start to follow an exercise interventionreported participation in another biomedical trial which may have an effect on blood parameters 1 month before the start of the studyblood donation in the past monthdiagnosis of cardiometabolic diseases such as diabetes mellitus or heart and vascular diseases.