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Not Yet Recruiting NCT05752058

Risk Factors for Early Acute Lung Injury After Liver Transplantation in Children

Conditions: Acute Lung Injury, Liver Transplantation, Risk Factors

Sex: All
Ages: 3 Months – 2 Years
Enrollment: 300
Sponsor: Tianjin First Central Hospital

Summary

The goal of this observational study is to identify the risk factors for early acute lung injury (ALI) after liver transplantation in children .The main questions it aims to answer are what the risk factors are for early ALI in children and to evaluate the predictive value for the development of ALI.Participants will be divided into non-ALI group and ALI group according to whether they had ALI in a week after liver transplantation.Researchers will compare the difference between the two groups and use multivariate logistic regression analysis to screen the risk factors of ALI, and receiver operating characteristic(ROC) curve was used to evaluate the predictive efficacy of risk factors.

Eligibility Criteria

Inclusion Criteria:patient was diagnosed with biliary atresiaAmerican society of anesthesiologists physical status Ⅱ-ⅢExclusion Criteria:Secondary liver transplantation or other important organ injury before surgeryPresent with congenital airway or respiratory malformationAcute respiratory infection or respiratory insufficiency was present within 1 month before surgeryIncomplete data

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05752058). StuddyBuddy aggregates publicly available trial information.