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NCT05750173
Replace Pre-TAVI ICA by Performing CTA
Conditions: Transcatheter Aortic Valve Implantation (TAVI)
Sex: All
Ages: 75 Years – N/A
Enrollment: 150
Sponsor: Institut für Pharmakologie und Präventive Medizin
Summary
ICA is not always required for a pre-TAVI workup of octogenarians and can be substituted by CTA resulting in a streamlined pre-procedural workup of patients without compromising patient safety.
Eligibility Criteria
Inclusion Criteria:Prospective CohortConsecutive adult patients ≥ 75 yearsConsecutive patients with severe AS (symptomatic or asymptomatic) with a guideline-based indication to undergo implantation of a transcatheter heart valve of the SAPIEN familyAbility to undergo CTAPatient is scheduled to undergo a 30 Day and 3 Months follow-upRetrospective CohortConsecutive adult patients ≥ 75 yearsConsecutive patients underwent implantation of a transcatheter heart valve of the SAPIEN family because of severe aortic stenosisPatients underwent both CTA and ICA before the procedurePatient underwent a 30 Day and 3 Months follow-upExclusion Criteria:Prospective CohortPatients with already diagnosed proximal stenosis of the left anterior descending artery (LAD) OR the left main coronary artery (LM) ≥50%Prior percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)Prior pacemaker implantation (PPI)Valve in valve intervention (ViV)Life expectancy below 12 monthsPatients without signed informed consent / data protection statement (according to requirements of local IRB/IEC)Retrospective CohortPatients diagnosed with proximal stenosis of the left anterior descending artery (LAD) OR the left main coronary artery (LM) ≥50% already at baselinePrior percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)Prior pacemaker implantation (PPI)Valve in valve intervention (ViV)Patients without signed informed consent / data protection statement (according to requirements of local IRB/IEC)
Source: ClinicalTrials.gov (NCT05750173). StuddyBuddy aggregates publicly available trial information.