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Active Not Recruiting
NCT05749770
Hormonal Contributors to COVID-19 Infection (COV-ENDO)
Conditions: COVID-19 Pandemic, Endocrine System Diseases
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: 1
Enrollment: 220
Sponsor: Istituto Auxologico Italiano
Location: Italy
Summary
The goal of this observational study is to measure the changes in the parameters of endocrine function and tissue sensitivity to hormones induced by SARs-CoV-2 infection.The main questions it aims to answer are:Does SARs-CoV-2 infection causes endocrine dysfunctions?Does the treatment of the underlying endocrine dysfunctions, improves the clinical outcome or the occurrence of late onset complications of SARs-CoV-2 infection?Are patients with previously known endocrine diseases more fragile in case of SARs-CoV-2 infection?
Participants will undergo blood testing and a physical examination at admission, during hospitalization at discharge and 3 and 6 moths after discharge They results will be compared to those of patients admitted for other reasons in order to assess whether the prevalence of endocrine dysfunctions is increased compared with controls.
Eligibility Criteria
Inclusion Criteria:Nasal swab positive for Sars-CoV-2Moderate to severe respiratory dysfunction due to COVID-19, requiring hospitalization.Exclusion Criteria:History of thyroid diseases before admissionHistory of adrenal diseasesHistory of hypogonadism (primary/secondary)History of pituitary diseases
Source: ClinicalTrials.gov (NCT05749770). StuddyBuddy aggregates publicly available trial information.