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NCT05748041
Multiparametric Approach to Identify a CMR-based Tricuspid Regurgitation Classification
Conditions: Tricuspid Regurgitation Congenital
Sex: All
Ages: 18 Years – N/A
Enrollment: 76
Sponsor: IRCCS Policlinico S. Donato
Location: Italy
Summary
The aims of this study are:to explore a novel 2D-Cardiovascular magnetic resonance (CMR) indirect method for tricuspid regurgitation (TR) quantification (ATRIAL method) relying on right atrium variables, and assess its agreement with the traditional indirect method (involving right ventricle variables) and the direct method (based on through-plane phase contrast (PC) sequences on the tricuspid valve);to assess the agreement of TR volume (RVol) and regurgitant fraction quantification from 2D-CMR methods with transthoracic echocardiography and 4DF-CMR methods;to assess the diagnostic performance of 2D-CMR in classifying TR, in terms of RVol and regurgitant fraction, with respect to echocardiographic transthoracic echocardiography grades.
Eligibility Criteria
Inclusion Criteria:patients aged ≥ 18 years with the diagnosis of al least mild-degree tricuspid regurgitation, who:patients that are scheduled for a Cardiovascular Magnetic Resonance examination in our InstitutionExclusion Criteria:Patients with previous surgical or transcatheter interventions on the tricuspid valvePatients with Ebstein's diseaseSubjects with pace-maker or intracardiac defibrillatorSubjects with intrabody ferromagnetic material precluding patient's safetyPatients with claustrophobia or breath-holding precluding an adequate CMR images qualityPregnant women
Source: ClinicalTrials.gov (NCT05748041). StuddyBuddy aggregates publicly available trial information.