The Efficacy of Neural Stimulation in Individuals With Schizophrenia

The purpose of this study is to understand the relationship between psychotic symptoms and social functioning in individuals with schizophrenia spectrum disorders. Our goal is to determine whether stimulating the brain using transcranial Direct Current Stimulation (tDCS) can improve symptoms and daily functioning.

Inclusion Criteria:Age = 18-60Diagnosed with schizophrenia or schizoaffective disorderHaving current (in the past week) or recent (in the past month) paranoiaExclusion Criteria:Presence or history of a pervasive developmental disorder or mental retardation as defined by IQ < 70Presence or history of neurological or medical disorders that contraindicate neural stimulation (e.g. presence or history of epilepsy, seizures, etc.)Demonstrating sensory limitations, including uncorrectable visual or hearing impairments that interfere with assessmentHistory of electroconvulsive therapyLack of proficiency in EnglishSubstance use disorder not in remission in the past 6 monthsAny implanted devices such as pace maker, neurostimulatorPregnancy