Colchicine for Reduction of Periprocedural Myocardial Injury in Percutaneous Coronary Intervention

Study of role of colchicine in reducing periprocedural myocardial injury in patients prepared for elective PCI and its role in reduction of MACEs.

Inclusion Criteria:Elective PCI in ACS patients with cardiac troponin peaked and stabilized and CCS patients .PP Myocardial Injury (Any increase in post-PCI troponin if pre-PCI troponin is negative or rise in post-PCI troponin above baseline pre-PCI troponin when it is peaked and stabilized).PPMI (rise in post-PCI troponin plus new evidence of ischemia).Exclusion Criteria:Patients with active infections.Patients taking anti-inflammatory medications.Patients presented with ACS( still rising troponin).Severe renal impairment ( creatinine clearance < 45 ml/min ).Primary PCI, rescue PCI, pharmacoinvasive therapy.Connective tissue diseases.