← Back to all trials
Active Not Recruiting
NCT05745792
Clinico-immunological Characterization and Immune Tolerance Breakdown in HU-autoimmunity
Conditions: Immune Tolerance
Sex: All
Enrollment: 400
Sponsor: Hospices Civils de Lyon
Location: France
Summary
Phenotypic characterization of patients with Hu-Abs, including the different neurological presentation and the presence or not of an underlying cancer.Analysis and clinical correlation of the diagnostic techniques for Hu-Abs detection (immunofluorescence, immunodot/Western blot, and CBA) in serum and/or CSF.Genomic and transcriptomic features of tumors (histological and immune infiltrate characteristics, transcriptomic profile, mutational status).
Eligibility Criteria
Inclusion Criteria * :Patient with neurological disorderPatient with Hu antibody in sera or CSFExclusion Criteria * :Patient with no dataPatient without neurological disorderPatient without Hu antibody in sera/CSF
Source: ClinicalTrials.gov (NCT05745792). StuddyBuddy aggregates publicly available trial information.
