Broccoli Seed Extract and Skin Health

The primary objective of this study is to examine the influence of 4-weeks ingestion of TrueBroc®, (broccoli seed extract, BSE) with mustard seed powder (MSP) on improving skin health by evaluating skin physiological and biochemical parameters. This study will test the effect of BSE and MSP compared to placebo on skin health after 4 weeks supplementation. The study will employ a randomized, crossover design with subjects acting as their own controls.

Inclusion Criteria:Both male and female subjects will be included, ages 25 to 57 years.Non-smoker and free of any medical conditions that might affect study measurements.Body mass index (BMI) of 20 - 29.9 kg/m2 (not obese).Willingness to adhere to dietary restrictions: refrain from consuming cruciferous vegetables (or related condiments and supplements) such as broccoli, cauliflower, cabbage, kale, bok choy, arugula, Brussels sprouts, collards, watercress, radishes, prepared mustard condiment, mustard greens, horseradish, wasabi, and mayonnaise for 3 days before and for the duration of the study.Willing to collect all urine for 24 hours and provide four blood samples on four separate occasions.Exclusion Criteria:Diarrhea or oral antibiotic intake within the last 4 weeks.Use of proton pump inhibitors (PPIs), antacids or other medications that influence stomach acidity.History of malabsorption or GI tract disorders or GI surgeries (i.e. lapband, gastric bypass, etc.).History of allergic reactions or intolerance to any of the ingredients contained in the test supplements (e.g. broccoli, broccoli seeds, mustard seeds, vitamin C).Currently pregnant, planning to become pregnant, or breastfeeding.Any other condition which in the Investigator's opinion may adversely affect the subject's ability to complete the study or its measures or which may pose significant risk to the subject.