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Recruiting NCT05743569

3D Specimen Maps for RT Planning

Conditions: Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Radiation Therapy

Sex: All
Ages: 28 Years – N/A
Enrollment: 13
Sponsor: Vanderbilt University Medical Center

Location: United States

Summary

The primary objective of this study is to measure the impact of patient-specific 3D specimen maps on adjuvant radiation treatment volumes and doses to critical organs. All patients will receive standard-of-care post-operative radiotherapy not impacted by the experimental 3D specimen maps. The secondary objective is to demonstrate the feasibility of incorporating 3D specimen mapping tools into post-operative communication, and to determine if utilization of the 3D specimen map improves post-operative communication between surgeons, pathologists, and radiation oncologists.

Eligibility Criteria

Inclusion Criteria:Over the age of 18Biopsy-confirmed mucosal head and neck cancer. All histologic malignancies will be included.Patients who have completed primary tumor surgical resection in the following anatomic subsites:oral cavity (oral tongue, floor of mouth, hard palate, buccal mucosa, retromolar trigone, maxillary and mandibular alveolus, lip)oropharynx (soft palate, base of tongue, palatine tonsils)hypopharynx (piriform sinus, post-cricoid, posterior pharyngeal wall)larynx (supraglottic, glottic, subglottic);Patients who have consented to 3D specimen mapping on protocol IRB # 221597 and for whom 3D specimen maps are therefore available.Patients are indicated to receive curative-intent post-operative radiotherapy and intend to receive radiotherapy at Vanderbilt University Medical Center or Vanderbilt Ingram Cancer Center sites in Nashville, Franklin, or LebanonExclusion Criteria:Under the age of 18Cutaneous malignanciesCharacteristics that make the process of informed consent questionablePregnant womenPatients with contraindications to radiotherapy

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05743569). StuddyBuddy aggregates publicly available trial information.