Pain and Microbial Reduction of Antimicrobial Corticosteroid Mixture Versus Cryotherapy in Necrotic Teeth

The aim of this study is to compare the effect of antimicrobial-corticosteroid mixture and cryotherapy as final root canal irrigating solutions on post-instrumentation pain in single-canal teeth with necrotic pulps.

Inclusion Criteria:Patients in good physical health; American Society of Anesthesiologists class I or II.Patients whose age ranges between 18 and 50 years.Male and female patients.Patients having a single canal-tooth with necrotic pulp.Patients who can understand the number rating scale (figure).Patients who accept to participate in the trial and can sign the informed consent (figure).Exclusion Criteria:Pregnant females.Patients with swelling.Patients whose tooth is non-restorable.Teeth with open apices.Teeth with radiographic evidence of root resorption.