Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia

Conditions: Aminophylline, Dexmedetomidine, Functional Endoscopic Sinus Surgery

Sex: All

Ages: 18 Years – 50 Years

Healthy volunteers: 1

Phase: NA

Enrollment: 52

Sponsor: Tanta University

Summary

This study will be conducted to evaluate the effect of intravenous aminophylline on hemodynamics and recovery of patients receiving dexmedetomidine infusion during functional endoscopic sinus surgery.

Eligibility Criteria

Inclusion Criteria:Patients aged between 18 to 50 years, have American society of anesthesiology (ASA) physical status I - II and scheduled for elective FESS under general anesthesia and receiving dexmedetomidine infusion for controlled hypotension during surgery.Exclusion Criteria:Patients with central nervous system diseases, cardiovascular diseases, hypertension, arrhythmias, cerebrovascular diseases, convulsions, renal impairment or hepatic dysfunction.Pregnancy or lactation.Patients with a history of allergy to aminophylline.Patients with recurrent sinus surgery, hypertension.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05738135). StuddyBuddy aggregates publicly available trial information.