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NCT05738096
Trigeminal Evoked Responses to Improve Rhizotomy
Conditions: Trigeminal Neuralgia, Rhizotomy
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: 1
Phase: EARLY_PHASE1
Enrollment: 30
Sponsor: University of Minnesota
Location: United States
Summary
Trigeminal neuralgia (TGN) is a debilitating pain syndrome where electrical, shock- like jolts of pain affect the face.
Trigeminal somatosensory evoked potentials (TSEPs) provide a promising modality for measuring the trigeminal sensory and nociceptive pathway by using peripheral stimulation of the trigeminal nerve (on the skin) and measuring low latency evoked potentials on the scalp (contralateral sensory cortex).
While TSEPs have been measured in the past, it is not clear if implementing TSEPs into a routine neurosurgical rhizotomy procedure will be feasible.
This is a prospective cohort study examining the feasibility of routinely performing TSEPs during rhizotomies for TGN.
Eligibility Criteria
Inclusion Criteria:Adults of 18 years or olderScheduled to undergo percutaneous rhizotomy for facial painExclusion Criteria:For TGN: Facial pain of unclear origin (i.e.
not clearly TGN pain) or Rhizotomy procedure canceledFor Healthy control: Diagnosis or history of facial pain such as TMD or TGN, History of migraine, History of any functional pain disorder: fibromyalgia, IBS, CRPS or Recent chronic pain (within last month)
Source: ClinicalTrials.gov (NCT05738096). StuddyBuddy aggregates publicly available trial information.