Early Prediction of Secondary Complications and Prognosis After aSAH

Aneurysmal subarachnoid haemorrhage (aSAH) is the most common and acute cerebrovascular disease, usually associated with a high mortality and morbidity, and with a 30% increased risk of re-rupture and a 50% increased risk of death from re-rupture.The early stage of brain injury after subarachnoid hemorrhage is usually accompanied by complications such as delayed cerebral ischemia (DCI), rebleeding, hydrocephalus, and other organ damage, of which DCI is the most common complication in patients with SAH, accounting for about 30%, often directly determining the functional outcome of patients with aSAH. Most clinically present with no other cause of neurologic deficit 4 to 14 days after bleeding, a decrease in GCS score of 2 points and lasting >1 hour, or a new well-circumscribed low-density focus on computed tomography that is absent immediately after surgery. Since the reversible nature of vasospasm after bleeding allows DCI to be reversible or develop into cerebral infarction, predicting DCI after aSAH within the time window is critical, which is of great significance for guiding antivasospasm and other clinical treatments and improving prognosis. Hence, it is urgently to predict secondary complications and functional outcome after aSAH, which plays an important role in recognizing low and hish-risk patients. It is of great significance to guide stepdown unit and reduce medical cost of patients in intensive care unit.

Inclusion Criteria:Subarachnoid hemorrhage was confirmed by CT;the CTA and DSA examination confirmed is aneurysm rupture caused by subarachnoid hemorrhage;bleeding after 24 hours of adept 38 blood routine, biochemical function, blood coagulation function and craniocerebral CT;DCI was observed during 3 to 14 days after surgery;aneurysm clip by surgery or endovascular embolization.Exclusion Criteria:Aneurysm rupture bleeding time more than 24 hours;by CTA and DSA examination found no intracranial aneurysm;Traumatic subarachnoid hemorrhage;the image data and check blood information is not complete;long-term anticoagulant drugs such as aspirin, wave dimensions;admitted to hospital with infectious diseases;merging other intracranial vascular malformation.