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Completed NCT05738070

Susceptibility Weighted Imaging for Detection of Thrombus in Acute Ischemic Stroke.

Conditions: Acute Ischemic Stroke

Sex: All
Enrollment: 105
Sponsor: Upendra Devokta Memorial National Institute of Neurology and Allied Scicences

Location: Nepal

Summary

It is a retrospective cross-sectional study, where consecutive stroke patients with vessel occlusion on magnetic resonance angiography (MRA) will be included for the study for one year. The relation of Susceptibility vascular sign (SVS) on Susceptibility Weighted Imaging (SWI) with risk factors and territory involved and length of thrombus will correlated with the National Institutes of Health stroke scale (NIHSS).Among total number of patients included in this study the demographics of the patients will be calculated. Risk factors for stroke of the patients included in this study will tabulated. The site of occlusion will be tabulated. The mean NIHSS scale will be calculated. Presence of SVS in patients with MR angiography positive vessel occlusion will be calculate in percentage. Subgroup analysis of presence of SVS on SWI will be done. The mean length of the thrombus will be calculated in these patients with positive SVS.Correlation between SVS on SWI with the risk factor of the patient by using the chi-square test will be calculated. A Chi-square test will be done to find out the correlation between the SVS with territorial occlusion. The correlation between the NIHSS score and length of thrombus will be calculated using the Pearson test.SWI can be useful in identifying the location of the thrombus, and NIHSS can determine the thrombus length in acute stroke. A higher incidence of SVS can be associated with risk factors and it also depends upon the site of occlusion of the vessel.

Eligibility Criteria

Inclusion Criteria:Anterior circulation stroke established by diffusion-weighted imaging (DWI),MRI performed within 72 hours of stroke onset,Patient with occlusion of the vessel on MRA (Magnetic Resonance Angiography).MRI performed before or during intravenous thrombolysis (IVT) or mechanical thrombectomy (MT).Exclusion Criteria:• Infarcts with hemorrhagic transformation cases were not included in the study due to suboptimal SVS quantification.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05738070). StuddyBuddy aggregates publicly available trial information.