← Back to all trials
Not Yet Recruiting
NCT05731765
SVP Detection Using Machine Learning
Conditions: Intracranial Pressure Increase
Sex: All
Ages: 18 Years – N/A
Healthy volunteers: 1
Enrollment: 210
Sponsor: King's College London
Summary
This diagnostic study will use 410 retrospectively captured fundal videos to develop ML systems that detect SVPs and quantify ICP.
The ground truth will be generated from the annotations of two independent, masked clinicians, with arbitration by an ophthalmology consultant in cases of disagreement.
Eligibility Criteria
Inclusion Criteria:Patients aged ≥18 years with presumed normal ICP undergoing routine dilated OCT scans.Patients undergoing a LP or continuous ICP monitoring with implanted transcranial pressure transducer devices at in- or out-patient neurology, neurosurgery or neuro-ophthalmology services.Exclusion Criteria:Glaucoma diagnosis or glaucoma suspects in either eye.Bilateral restricted fundal view, e.g.
advanced bilateral cataracts.Bilateral retinal vein or artery occlusion.
Source: ClinicalTrials.gov (NCT05731765). StuddyBuddy aggregates publicly available trial information.