From the Gut to the Strut: Reducing Inflammation for Healthy Muscles

This research aims to evaluate the effectiveness of a dietary supplement on reducing inflammation and improving muscle health. The product is a food supplement notified to the Ministry of Health consisting of: hydroxymethylbutyrate, carnosine, lactoferrin and magnesium, which help reduce inflammation and intestinal permeability and to improve muscle health.

Inclusion Criteria:sarcopenic patients aged 55-85. Sarcopenia will be diagnosed according to the European Working Group on Sarcopenia in Older People (EWSGOP-2) criteria by muscle strength or chair stand test.Exclusion Criteria:severe kidney disease (glomerular filtration rate <30 mL/min),moderate-to-severe hepatic failure (Child-Pugh Class of B or C),endocrine diseases associated with disorders of calcium metabolism (with the exception of osteoporosis),psychiatric disorders,cancer (in the previous 5 years),hypersensitivity to any investigational food componentsubjects taking protein/amino acid supplements (up to 3 months prior to the study).patients not capable of taking oral therapy and those receiving or having indication for artificial nutrition or included in another clinical nutrition trial